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Effects of QSN-10c on mitochondrial membrane potential and expression of mitochondria-related apoptotic proteins. (A–B) The mitochondrial membrane potential of K562 cells treated with QSN-10c was decreased in a dose-dependent manner. (C) Treatment of cells with various concentrations of QSN-10c for 48 h resulted in dose-dependent increase in the release of cytochrome c, and in the expression of Bax. The level of Bcl-2 was decreased in a dose-dependent manner.
