Figure 2.

Schematic representation of the influence of host Lf on immune cells. (a) Promotes B- and T-lymphocyte maturation; (b) Negative regulation of B-lymphocytes through LPS binding; (c) B- and T-lymphocyte interaction; (d) induces IgA and IgG secretion; (e) promotes T-lymphocyte proliferation; (f) decreases IL5 and IL10 secretion; (g) down regulates NFκβ activation of monocytes; (h) enhances the phagocytic activity of macrophages; and (i) prevents the interaction between LPS and CD14 as a TLR4. B, B lymphocytes; T, T lymphocytes; Mf, macrophages; Mon, Monocytes; Neu, Neutrophils.