Figure 2.

Effects of C-K on the body weight and arthritis scores of CIA mice. DBA/1 mice were immunized with CII and FCA on d 0 and d 21. The mice were then treated with C-K (28, 56, or 112 mg/kg, ig, qd, for 34 d) or methotrexate (MTX, 2 mg/kg, ig, every 3 d, for 34 d). Data are expressed as the mean±SD. n=10. ^bP<0.05, ^cP<0.01 vs normal mice. ^eP<0.05, ^fP<0.01 vs CIA mice.