Table 1. Genotype and allele distribution for IL18 polymorphisms in seronegative and seropositive individuals.
| Genotype. N (%) | Allele test | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| SNP | 1|2 | Group (N) | 1|1 | 1|2 | 2|2 | MAF % | P | P* | OR [95% CI] |
| rs5744258 | C|G | Seronegative (592) | 5 (0.84) | 127 (21.45) | 460 (77.70) | 11.57 | |||
| Seropositive (570) | 2 (0.35) | 128 (22.46) | 440 (77.19) | 11.58 | 0.9952 | 0.9952 | 1.00 [0.78–1.29] | ||
| rs360722 | T|C | Seronegative (591) | 7 (1.18) | 123 (20.81) | 461 (78.00) | 11.59 | |||
| Seropositive (572) | 11 (1.92) | 119 (20.80) | 442 (77.27) | 12.33 | 0.5850 | 0.7021 | 1.07 [0.83–1.38] | ||
| rs2043055 | C|T | Seronegative (591) | 74 (12.52) | 276 (46.70) | 241 (40.78) | 35.87 | |||
| Seropositive (568) | 98 (17.25) | 281 (49.47) | 189 (33.27) | 41.99 | 2.52E-03 | 5.04E-03 | 1.29 [1.10–1.53] | ||
| rs187238 | C|G | Seronegative (590) | 101 (17.12) | 276 (46.78) | 213 (36.10) | 40.51 | |||
| Seropositive (572) | 67 (11.71) | 259 (45.28) | 246 (43.01) | 34.55 | 2.18E-03 | 5.04E-03 | 0.77 [0.65–0.91] | ||
| rs1946518 | C|A | Seronegative (588) | 123 (20.92) | 309 (52.55) | 156 (26.53) | 47.19 | |||
| Seropositive (572) | 157 (27.45) | 283 (49.48) | 132 (23.08) | 52.19 | 0.0162 | 0.0243 | 1.22 [1.04–1.44] | ||
| rs360719 | C|T | Seronegative (593) | 101 (17.03) | 280 (47.22) | 212 (35.75) | 40.64 | |||
| Seropositive (572) | 67 (11.71) | 258 (45.10) | 247 (43.18) | 34.27 | 1.49E-03 | 5.04E-03 | 0.76 [0.64–0.90] | ||