Table 4. IL18 haplotype analysis of seropositive and seronegative individuals.
| Seropositive | Seronegative | |||||||
|---|---|---|---|---|---|---|---|---|
| Haplotype | N | (%) | N | (%) | P | *PFDR | **PPERM | OR [95% CI] |
| TCAC | 391 | 34.10 | 479 | 40.50 | 1.50E-03 | 7.50E-03 | 4.90E-03 | 0.76 [0.65–0.90] |
| CGCT | 458 | 40.00 | 413 | 35.00 | 0.0116 | 0.0290 | 0.0428 | 1.25 [1.05–1.47] |
| TGCT | 138 | 12.10 | 144 | 12.20 | 0.9222 | 0.9222 | 1.000 | 0.99 [0.77–1.27] |
| TGAT | 137 | 12.00 | 134 | 11.30 | 0.6148 | 0.7685 | 0.9758 | 1.00 [0.89–1.12] |
| CGAT | 18 | 1.60 | 12 | 1.00 | 0.2262 | 0.3770 | 0.6380 | 1.52 [0.74–3.13] |
‡Order of SNPs: rs2043055|rs187238|rs1946518|rs360719
*P value after Benjamini & Hochberg step-up false discovery rate correction.
**Permutation test P-value for 10,000 permutations.