Fig 2. Mecamylamine significantly decreased sucrose intake in rats consuming sucrose short-term (4 weeks) and long-term (12 weeks) using the intermittent-access two-bottle choice paradigm.

Mecamylamine (2 mg/kg) significantly decreased sucrose consumption in short-term (4 weeks) and long-term (12 weeks) sucrose exposure rats (Fig 2A and 2B). The values are expressed as mean sucrose consumed (g/kg) ± SEM (repeated-measures ANOVA followed by Newman—Keuls post hoc test). *, P < 0.05; **, P < 0.01; ***, P < 0.001 compared with vehicle, n = 12.