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. Author manuscript; available in PMC: 2017 Mar 2.
Published in final edited form as: Chembiochem. 2016 Feb 3;17(5):383–387. doi: 10.1002/cbic.201500586

Figure 2.

Figure 2

Enzymatic activation of CEST MRI contrast agent with sulfatase and esterase. The agent is designed to be converted to salicylic acid only after serial treatment with each enzyme, or simultaneous treatment with both enzymes.