Figure 16.

Glomeruli are preserved in CP mice. (A) Box and whisker plot shows that the density of glomeruli per unit volume of kidney cortex was significantly increased in CP mice (n=3) versus control mice (n=3) (P<0.001). (B) The average cortical non–glomerular cell cross-sectional area in midcoronal optical sections was significantly decreased in CP mice (n=28/group from 4 mice/group; P<0.001). (C) In contrast, the glomerular cross-sectional area in same sections was not significantly different between groups (P=0.12). Error bars in (B) and (C), ±SEM.