Figure 5.

Traditional histology shows few morphologic changes other than reduced overall kidney size in response to two doses of cisplatin. Low-power coronal hematoxylin and eosin–stained kidney sections of normal control (A) and CP kidneys (C) show relative reduction in the overall diameter of the post-cisplatin kidney without overt architectural changes. Corresponding high-power images for normal (B) and CP (D) kidneys show no systematic histologic changes in glomeruli or tubules that can be readily identified. Scale bar=50 μm.