Table 2.
Comparison of two datasets of plasma samples from lung cancer patients
| Reference data set exon 19 deletion (IIIB–IV) | Reference data set L858R (IIIB–IV) | Analysis data set exon 19 deletion | Analysis data set L858R | Analysis data set T790M | |
|---|---|---|---|---|---|
| Plasma‐positive samples | |||||
| <100 | 0 | 1 | 6 | 7 | 5 |
| 100–999 | 6 | 10 | 26 | 17 | 18 |
| 1000–9999 | 11 | 7 | 7 | 16 | 7 |
| >10 000 | 8 | 5 | 7 | 7 | 2 |
| Total | 25 | 23 | 46 | 47 | 32 |
| All samples | |||||
| Total | 36 | 30 | 83 | 92 | 190 |
| Detection rate in plasma, % | 69.4 | 76.7 | 55.4 | 51.1 | 16.8 |
Analysis set comprised 190 plasma samples from 57 patients taken during their treatment course. The reference dataset was obtained from a multi‐institute prospective study14 that comprised a uniform population for comparison of genotyping of plasma and biopsy samples. The plasma‐positive samples were grouped according to PM score range.