Skip to main content
. 2016 Feb 18;107(3):250–257. doi: 10.1111/cas.12865

Figure 5.

Figure 5

Hemoglobin‐coating or holo‐transferrin‐coating of multi‐wall carbon nanotubes (MWCNT) induces DNA damage to rat peritoneal mesothelial cells without causing apoptosis. We used a comet assay to determine whether protein coating may cause DNA damage in rat peritoneal mesothelial cells. Tail length (a). Tail moment (b). Examples of scoring in comet assay (c). We observed a significant increase in dead cells, presumably through apoptosis, only when lung lysate was used to coat NT50 after 4 or 8 h of incubation (d; N=3, means ± SEM; *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001 vs control otherwise specified; NS, not significant).