Table 1.

Transport of [¹⁴C]FAMT and [¹⁴C]Met by amino acid transporters

Amino acid transport system	Transporter	Gene	[14C]FAMT	[14C]Met
L	LAT1	SLC7A5	+†	+‡
L	LAT2	SLC7A8	−	+
L	LAT3	SLC43A1	−	+
L	LAT4	SLC43A2	−	+
T	TAT1	SLC16A10	−	−
B0	B0AT1	SLC6A19	−	+
B0,+	ATB0,+	SLC6A14	−	+
b0,+†			−	+
y+L	y+LAT1	SLC7A7	−	+
y+L	y+LAT2	SLC7A6	−	+
ASC	ASCT1	SLC1A4	−	−
ASC	ASCT2	SLC1A5	−	+
N/A	SNAT1	SLC38A1	−	+
N/A	SNAT2	SLC38A2	−	+
N/A	SNAT3	SLC38A3	−	+
N/A	SNAT4	SLC38A4	−	+
N/A	SNAT5	SLC38A5	−	+

†“+” indicates that [¹⁴C]FAMT or [¹⁴C]Met is transported by the designated transporter, whereas “−” indicates that [¹⁴C]FAMT or [¹⁴C]Met is not transported. ‡b^0,+ activity was induced by expressing rBAT (SLC3A1), an auxiliary subunit of system b^0,+ transporter, in Xenopus oocytes (see the legend to Fig. 2).