Table 2.
Discriminant analysis for breast cancer
| Discriminant | Training cohort | Test cohort | ||||
|---|---|---|---|---|---|---|
| Accuracy (%) | Sensitivity (%) | Specificity (%) | Accuracy (%) | Sensitivity (%) | Specificity (%) | |
| Diagnostic index with five miRNAs | 78.7 | 87.8 | 78.5 | 89.7 | 97.3 | 82.9 |
| miR‐1246 | 63.8 | 81.1 | 63.2 | 91.0 | 88.3 | 93.4 |
| miR‐1307‐3p | 57.8 | 51.4 | 58 | 75.3 | 100 | 53.1 |
| miR‐4634 | 50.9 | 58.1 | 50.7 | 40.4 | 3.4 | 73.6 |
| miR‐6861‐5p | 63.2 | 62.2 | 63.3 | 89.1 | 99.8 | 79.4 |
| miR‐6875‐5p | 73.7 | 77 | 73.6 | 47.4 | 14.7 | 76.8 |
The diagnostic index was calculated using the following formula: (0.25 × miR‐1246) + (0.49 × miR‐1307‐3p) − (1.06 × miR‐4634) + (1.89 × miR‐6875‐5p) + (0.31 × miR‐6861‐5p) − 13.94.