Table 1.

Potential targets of miR-8 tested in the 3′UTR reporter assay. Potential targets conserved with the miR-200 family in human cells were identified in Bracken et al., EMBO J, vol. 33 p 2040, 2014.

Drosophila gene	function	Human homolog	Conserved target?
jaguar (jar)	Atypical myosinVI	MYO6	Mir-200a coding
peanut (pnut)	septin	SEPT7	-
Sra-1	Arp2/3-dependent actin polymerization	CYFIP1/2	-
enabled (ena)	Actin polymerization	ENAH/VASP	-
Actin binding protein 1 (Abp1)	Actin binding	DBNL/DBN1	-
spaghetti squash (sqh)	Myosin regulatory light chain	MYL12A/B, MYL9	MYL Kinase targeted by Mir-200c
Calpain-A (CalpA)	Ca2+-dependent cysteine endopeptidase	CAPN9/2/3/1	Mir-200b 3′UTR
Actin-related protein (Arp3)	Arp2/3 complex, actin polymerization	ACTR3/3B/3C	Mir-200a 3′UTR
Van Gogh (Vang)	Planar polarity/Frizzled binding	VANGL1/2	Mir-200b 3′UTR