Table 3.
Incidence of cardiovascular disease according to different types of physical activity among older US adults, stratified by age and gender *.
| Hazard ratios (95% confidence intervals) for Cardiovascular Disease | ||||||||
|---|---|---|---|---|---|---|---|---|
| Nº of incidence/total | 698/2926 | 484/1281 | 546/1633 | 636/2574 | ||||
| <75 years (69.4±2.6) | p | ≥75 years (79.3±3.9) | p | Men | p | Women | p | |
| Walking pace, mph | ||||||||
| < 2 | Reference | Reference | Reference | Reference | ||||
| 2–3 | 0.67(0.56,0.79) | <0.001 | 0.69(0.57,0.83) | <0.001 | 0.64(0.53,0.77) | <0.001 | 0.70(0.59,0.84) | <0.001 |
| > 3 | 0.52(0.40,0.67) | <0.001 | 0.39(0.24,0.64) | <0.001 | 0.48(0.35,0.66) | <0.001 | 0.52(0.37,0.72) | <0.001 |
| P trend | <0.001 | <0.001 | <0.001 | <0.001 | ||||
| Walking distance, blocks/week | ||||||||
| 0–5 | Reference | Reference | Reference | Reference | ||||
| 6–12 | 0.67(0.51,0.88) | 0.004 | 0.75(0.58,0.96) | 0.023 | 0.52(0.38,0.71) | <0.001 | 0.80(0.64,1.00) | 0.052 |
| 13–25 | 0.67(0.52,0.86) | 0.002 | 0.69(0.53,0.90) | 0.006 | 0.55(0.41,0.73) | <0.001 | 0.73(0.57,0.92) | 0.007 |
| 26–48 | 0.55(0.42,0.71) | <0.001 | 0.58(0.43,0.80) | 0.001 | 0.43(0.32,0.58) | <0.001 | 0.63(0.48,0.83) | 0.001 |
| ≥49 | 0.58(0.44,0.75) | <0.001 | 0.43(0.30,0.61) | <0.001 | 0.39(0.29,0.53) | <0.001 | 0.69(0.52,0.92) | 0.011 |
| P trend | <0.001 | <0.001 | <0.001 | 0.001 | ||||
| Walking Score† | ||||||||
| I | Reference | Reference | Reference | Reference | ||||
| II | 0.79(0.61,1.01) | 0.062 | 0.71(0.57,0.90) | 0.004 | 0.57(0.43,0.75) | <0.001 | 0.84(0.68,1.03) | 0.093 |
| III | 0.53(0.41,0.69) | <0.001 | 0.59(0.46,0.77) | <0.001 | 0.42(0.32,0.56) | <0.001 | 0.62(0.49,0.78) | <0.001 |
| IV | 0.53(0.40,0.70) | <0.001 | 0.32(0.21,0.47) | <0.001 | 0.34(0.25,0.46) | <0.001 | 0.59(0.44,0.79) | <0.001 |
| P trend | <0.001 | <0.001 | <0.001 | <0.001 | ||||
| Leisure-time activity, kcal/week | ||||||||
| I | Reference | Reference | Reference | Reference | ||||
| II | 0.69(0.54,0.89) | 0.004 | 0.74(0.56,0.96) | 0.025 | 0.64(0.46,0.90) | 0.008 | 0.74(0.59,0.92) | 0.008 |
| III | 0.62(0.48,0.80) | <0.001 | 0.69(0.53,0.91) | 0.009 | 0.55(0.40,0.76) | <0.001 | 0.69(0.55,0.87) | 0.002 |
| IV | 0.74(0.58,0.95) | 0.017 | 0.65(0.49,0.87) | 0.004 | 0.62(0.46,0.84) | 0.002 | 0.76(0.60,0.97) | 0.025 |
| V | 0.59(0.46,0.77) | <0.001 | 0.55(0.40,0.76) | <0.001 | 0.54(0.40,0.73) | <0.001 | 0.56(0.41,0.77) | 0.001 |
| P trend | 0.003 | <0.001 | 0.003 | 0.001 | ||||
| Exercise Intensity† | ||||||||
| None | Reference | Reference | Reference | Reference | ||||
| Low | 0.61(0.45,0.84) | 0.002 | 0.65(0.48,0.87) | 0.004 | 0.73(0.50,1.04) | 0.087 | 0.60(0.46,0.78) | <0.001 |
| Moderate | 0.54(0.39,0.74) | <0.001 | 0.58(0.42,0.79) | 0.001 | 0.63(0.43,0.92) | 0.015 | 0.54(0.41,0.72) | <0.001 |
| High | 0.49(0.33,0.73) | <0.001 | 0.30(0.15,0.60) | 0.001 | 0.61(0.39,0.98) | 0.040 | 0.35(0.21,0.56) | <0.001 |
| P trend | 0.001 | <0.001 | 0.022 | <0.001 | ||||
For each analysis participants with prevalent disease at baseline were excluded. All analyses are adjusted for age (years), gender (male/female), race (white/nonwhite), education (< high school, high school, > high school), income (≤/> $ 25,000/yr), clinical sites (four categories), smoking (never, former, current), body mass index (kg/m2). All physical activity variables were updated over time.
See text and Supplementary Figure 1 for details on how the physical activity variables were defined.