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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Curr Drug Targets. 2016;17(9):1029–1050. doi: 10.2174/1389450116666151001105622

Figure 12.

Figure 12

Proposed Catalytic Mechanism for B1 MBLs. Only the essential catalytic zinc and D120 features are shown in a proposed hydrolysis mechanism of a cephem. Dashed lines indicate proposed interactions that facilitate binding and catalysis.