Table 1.
Summary of study characteristics
| Studies | Design | Country | Sample size | Sex (M/F) | Mean age (years) | Surgical levels | Prostheses/manufacturers | Followup (months) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CDA | ACDF | CDA | ACDF | CDA | ACDF | ||||||
| Burkus et al. [5] | RCT | USA | 276 | 265 | 128/148 | 122/143 | 43 | 44 | 1 | Prestige® ST/Medtronic Sofamor Danek, Memphis, TN, USA | 84 |
| Coric et al. [8] | RCT | USA | 136 | 133 | 51/85 | 59/74 | 44 ± 8 | 44 ± 7 | 1 | Kineflex|CTM/Spinal Motion Inc, Mountain View, CA, USA | 24 |
| Davis et al. [10] | RCT | USA | 225 | 105 | 113/112 | 45/60 | 45 ± 8 | 46 ± 8 | 2 | Mobi-C®/LDR Medical, Troyes, France | 48 |
| Hisey et al. [22] | RCT | USA | 164 | 81 | 78/86 | 36/45 | 43 ± 9 | 44 ± 8 | 1 | Mobi-C®/LDR Medical, Troyes, France | 48 |
| Phillips et al. [30] | RCT | USA | 218 | 185 | 113/105 | 96/89 | 45 ± 9 | 44 ± 8 | 1 | PMC ®/NuVasive Inc, San Diego, CA, USA | 24 |
| Rožanković et al. [34] | RCT | Croatia | 51 | 50 | 25/26 | 25/25 | 41 ± 9 | 42 ± 9 | 1 | Discover ®/DePuy Spine, Raynham, MA, USA | 24 |
| Sasso et al. [35] | RCT | USA | 242 | 221 | 110/132 | 113/108 | 44 | 45 | 1 | Bryan®/Medtronic Sofamor Danek, Memphis, TN,USA | 48 |
| Skeppholm et al. [37] | RCT | Sweden | 81 | 70 | 40/41 | 33/37 | 47 ± 7 | 47 ± 7 | 1 or 2 | Discover®/DePuy Spine, Raynham, MA, USA | 24 |
| Vaccaro et al. [38] | RCT | USA | 151 | 140 | 81/70 | 68/72 | 43±8 | 44 ± 8 | 1 | SECURE®-C/Globus Medical, Audubon, PA, USA | 24 |
| Zhang et al. [42] | RCT | China | 55 | 56 | 25/30 | 26/30 | 45 | 47 | 1 | Mobi-C®/LDR Medical, Troyes, France | 48 |
| Zhang et al. [43] | RCT | China | 60 | 60 | 35/25 | 32/28 | 45 ± 6 | 46 ± 6 | 1 | Bryan®/Medtronic Sofamor Danek, Memphis, TN,USA | 24 |
| Zigler et al. [44] | RCT | USA | 103 | 106 | 49/57 | 46/57 | 42 ± 8 | 44 ± 7 | 1 | ProDisc®-C / Synthes Inc, West Chester, PA,USA | 60 |
CDA = cervical disc arthroplasty; ACDF = anterior cervical discectomy and fusion; RCT = randomized controlled trial.