Skip to main content
. 2016 Mar 31;10:126. doi: 10.3389/fnins.2016.00126

Table 3.

Number of cortical neurons belonging to different morphological types in rats exposed to hypoxia on E18.

Type of cells Days after birth
P10 P20 P30 P60 P90
The number of cortical cells in rats exposed to hypoxia on E18 in % to control
Small non-pyramidal 97.1 ± 12.6 110.4 ± 11.2 100.0 ± 11.5 92.0 ± 10.1 115.8 ± 21.1
Big non-pyramidal 95.0 ± 15.3 95.7 ± 10.5 115.6 ± 8.8 94.5 ± 7.8 99.7 ± 17.4
Small pyramidal 104.3 ± 5.8 101.4 ± 8.2 92.4 ± 15.2 115.1 ± 19.9 92.8 ± 15.2
Big pyramidal 102.8 ± 3.7 110.6 ± 11.6 108.4 ± 7.2 100.0 ± 4.4 97.9 ± 15.5
Total cell number 100.5 ± 4.4 99.1 ± 3.8 90.7 ± 9.8 105.2 ± 9.4 105.0 ± 9.2
GFAP-positive cells 101.7 ± 3.2 104.6 ± 4.8 105.2 ± 6.7 104 ± 6.4 94.7 ± 8.9
Fox3 (NeuN)-positive 96.8 ± 8.4 108.5 ± 9.6 91.4 ± 11.5 93.5 ± 7.7 94.1 ± 10.5

Neural cells were classified by their size (area) and shape (ratio of the longest to the shortest axes) of the cell body. Data are presented as the ratio (mean number of cells in rats exposed to hypoxia/mean number of cells in control rats) in % ± Standard error of the difference between the means of two samples. 100%—cell number in control rats. In each group of animals (n = 8) 10 cortical tissue areas of each animal were analyzed by Nissl staining or immunohistochemistry. No changes (compared to control) in rats, exposed to hypoxia on E18, were observed.