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Exosomes and MV main differences in biogenesis, properties, and functions.
| Vesicle type | Properties | Biogenesis | Function | |
|---|---|---|---|---|
| Size | Lipids | |||
| Exosomes | 50–200 nm | Ceramide | Late endosome (MVB) | Horizontal transmission of RNA and proteins |
| Microvesicles | 50–1000 nm | Phosphatydilserine | Plasma membrane | Horizontal Transmission of DNA and RNA |
| Apoptotic bodies | 500–2000 nm | Phosphatydilserine | Plasma membrane | Not yet reported |
