Table 1.

Summary of similarities between eye tracking studies in conventional radiography and in volumetric imaging, unique challenges of eye tracking studies regarding the volumetric imaging context and proposed actions to overcome these.

Issues	Similarities conventional radiography and volumetric imaging	Challenges unique to the volumetric imaging context	Actions to overcome challenges in volumetric imaging
Stimulus material	Issues of standardization	Free scrolling adds factor to study	Weighing of experimental rigor and ecological validity
		Multitude of options to manipulate images	Only one manipulation at a time
Event detection	Event detection based on physiological properties of eye movements	Smooth pursuit eye movements	Velocity based event detection or use of raw data after elimination of saccades
		Events cover multiple slices	Customized software that maps proportions of events to slices
Parameter calculation	Similar parameters can be used to study visual search	Positioning of AOI in case introduces variability	Calculation of parameters directly related to event
		Meaning of parameters may change	More research is needed, time will tell
		Scrolling behavior is not covered by conventional parameters	New parameters are being developed, further research is needed for their validation
Reporting abnormalities	(JAF) ROC studies are suitable	Orientation within case can be tricky	Visible marking of reported lesions
		Reporting interferes with eye tracking	Tracking of reporting to separate perceptual and decision making processes