Figure 3. Preliminary ligand screen in the nickel-catalysed monoarylation of ammonia.

Reactions employed 4-chlorobiphenyl (0.12 mmol), 0.5 M stock solutions of ammonia in 1,4-dioxane (0.72 ml) and toluene (1.00 ml). Conversions estimated on the basis of gas chromatographic data, reported as % 4-aminobiphenyl (% 4-chlorobiphenyl unreacted); mass balance attributable to biphenyl and/or other unidentified products; COD, 1,5-cyclooctadiene.