Table 3.
Factors associated with postoperative hepatocellular carcinoma recurrence and hepatocellular carcinoma-related death on multivariate Cox regression analysis
| Variables | HR | 95% CI | P value |
|---|---|---|---|
| Risk of recurrence | |||
| HBV DNA load (positive vs negative) | 1.40 | 0.73–2.68 | 0.309 |
| Hilar clamping time (>18 min vs ≤18 min) | 1.93 | 1.02–3.64 | 0.043* |
| Tumor diameter (>10 cm vs ≤10 cm) | 1.57 | 0.77–3.17 | 0.212 |
| Tumor satellites (yes vs no) | 2.17 | 1.12–4.20 | 0.021* |
| PVTT type (III/IV vs I/II) | 2.20 | 1.05–4.62 | 0.038* |
| Surgical type (thrombectomy vs en-bloc resection) | 1.41 | 0.72–2.75 | 0.319 |
| Preoperative examination (3D imaging vs MSCT) | 0.49 | 0.27–0.90 | 0.021* |
| Risk of HCC-related death | |||
| HBV DNA load (positive vs negative) | 2.22 | 1.20–4.12 | 0.011* |
| Hilar clamping time (>18 min vs ≤18 min) | 1.49 | 0.79–2.80 | 0.220 |
| Major postoperative complication | 1.13 | 0.49–2.60 | 0.772 |
| Tumor diameter (>10 cm vs ≤10 cm) | 2.16 | 1.13–4.11 | 0.019* |
| PVTT type (III/IV vs I/II) | 3.64 | 1.65–8.04 | 0.001* |
| Surgical type (thrombectomy vs en-bloc resection) | 0.88 | 0.39–1.98 | 0.753 |
| Preoperative examination (3D imaging vs MSCT) | 0.41 | 0.21–0.78 | 0.007* |
HR, hazard ratio; CI, confidential interval; HBV, hepatitis B virus; PVTT, portal vein tumor thrombus; 3D, three-dimensional MSCT, multiple-slice computed tomography.
* P < 0.05.