Table 2.

Prognostic factors for overall survival

	Variable	Est. median survival (months)	Cox regression
Univariable HR (95% CI)	P-value	Multivariable HR (95% CI)	P-value
Blood transfusion	No	49	Reference	0.461	Reference	0.993
	Yes	41	1.18 (0.76–1.83)		1.00 (0.59–1.68)
Age	Per year	NA	1.00 (0.98–1.02)	0.651	0.99 (0.96–1.01)	0.150
Sex	Female	47	Reference	0.474	Reference	0.854
	Male	47	1.18 (0.75–1.84)		1.05 (0.63–1.74)
Type of resection	No major hepatectomy	41	Reference	0.516	Reference	0.890
	Major hepatectomy	48	0.86 (0.55–1.35)		1.04 (0.61–1.76)
Portal vein reconstruction	No	46	Reference	0.057	Reference	0.028
	Yes	NAa	0.51 (0.25–1.02)		0.43 (0.20–0.91)
Margin	R0	49	Reference	0.099	Reference	0.015
	R1	38	1.46 (0.93–2.28)		1.93 (1.14–3.28)
Lymph node metastases	N0	49	Reference	0.001	Reference	0.001
	N1	27	2.27 (1.38–3.73)		2.49 (1.17–4.28)
Tumor differentiation	Well	68	Reference	0.009	Reference	0.014
	Moderate/poor	38	2.21 (1.22–4.02)		2.15 (1.17–3.96)
Major complications	No	49	Reference	0.185	Reference	0.218
	Yes	29	1.36 (0.86–2.15)		1.37 (0.83–2.28)

HR, hazard ratio; CI, confidence interval; NA, not available.

^aThe median survival in patients with PV reconstruction is not available, this is because more than half of the patients is alive. The median has not been reached.