Table 2.
Distribution of genotype frequencies between the groups.
| Gene/SNP ID* | DA+ (n = 95) n (%) |
AWs (n = 142) n (%) |
Fisher’s exact p values |
|---|---|---|---|
| ADAM33 S1 (rs3918396) | |||
| 1.1 | 75 (80.6) | 122 (85.9) | 0.3661 |
| 1.2 | 13 (14.0) | 17 (12.0) | |
| 2.2 | 5 (5.4) | 3 (2.1) | |
| ADAM33 ST + 5 (rs597980) | |||
| 1.1 | 23 (24.5) | 41 (28.9) | 0.5444 |
| 1.2 | 50 (53.2) | 65 (45.8) | |
| 2.2 | 21 (22.3) | 36 (25.3) | |
| ADAM33 T1 (rs2280091) | |||
| 1.1 | 70 (74.5) | 113 (80.1) | 0.1681 |
| 1.2 | 22 (23.4) | 28 (19.9) | |
| 2.2 | 2 (2.1) | 0 (0.00) | |
| ALOX5 (G-1699A) (rs4986832) | |||
| 1.1 | 59 (64.1) | 95 (66.9) | 0.7180 |
| 1.2 | 28 (30.4) | 42 (29.6) | |
| 2.2 | 5 (5.4) | 5 (3.5) | |
| PTGS1 (C644A) (rs5788) | |||
| 1.1 | 69 (73.4) | 102 (72.3) | 0.7237 |
| 1.2 | 20 (21.3) | 34 (24.1) | |
| 2.2 | 5 (5.3) | 5 (3.6) | |
| PTGS2 (G-765C) (rs20417) | |||
| 1.1 | 65 (69.1) | 91 (64.5) | 0.0566 |
| 1.2 | 23 (24.5) | 48 (34.0) | |
| 2.2 | 6 (6.4) | 2 (1.4) | |
| PTGS2 (G3050C) (rs5277) | |||
| 1.1 | 68 (72.3) | 105 (74.5) | 0.3547 |
| 1.2 | 26 (27.2) | 33 (23.4) | |
| 2.2 | 0 (0.00) | 3 (2.1) | |
| NAG1/GDF15 (H6D) (rs1058587) | |||
| 1.1 | 49 (52.1) | 76 (53.9) | 0.8561 |
| 1.2 | 41 (43.6) | 57 (40.4) | |
| 2.2 | 4 (4.3) | 8 (5.7) | |
| NAG1/GDF15 (V9L) (rs1059519) | |||
| 1.1 | 41 (43.6) | 56 (39.4) | 0.6283 |
| 1.2 | 41 (43.6) | 71 (50.0) | |
| 2.2 | 12 (12.8) | 15 (10.6) | |
| IL10 (G-1082A) (rs1800896) | |||
| 1.1 | 27 (29.0) | 39 (27.5) | 0.3051 |
| 1.2 | 45 (48.4) | 81 (57.0) | |
| 2.2 | 21 (22.6) | 22 (15.5) | |
| IL10 (C-819T) (rs1800871) | |||
| 1.1 | 56 (60.2) | 72 (51.1) | 0.4177 |
| 1.2 | 31 (33.3) | 57 (40.4) | |
| 2.2 | 6 (6.5) | 12 (8.5) | |
| IL1α (G + 4845T) (rs17561) | |||
| 1.1 | 45 (48.4) | 78 (54.9) | 0.5935 |
| 1.2 | 38 (40.9) | 51 (35.9) | |
| 2.2 | 10 (10.7) | 13 (9.2) | |
| IL1β (C + 3953T) (rs1143634) | |||
| 1.1 | 48 (51.6) | 88 (62.0) | 0.0635 |
| 1.2 | 43 (46.2) | 46 (32.4) | |
| 2.2 | 2 (2.2) | 8 (5.6) | |
| IL1β (C-511T) (rs16944) | |||
| 1.1 | 38 (40.9) | 63 (44.4) | 0.8735 |
| 1.2 | 40 (43.0) | 58 (40.8) | |
| 2.2 | 15 (16.1) | 21 (14.8) | |
| IL1 RN (T + 2018C) (rs419598) | |||
| 1.1 | 50 (53.2) | 75 (52.8) | 1.0000 |
| 1.2 | 37 (39.4) | 56 (39.4) | |
| 2.2 | 7 (7.4) | 11 (7.8) | |
| TGFB (C-509T) (rs1800469) | |||
| 1.1 | 53 (57.0) | 63 (44.4) | 0.1693 |
| 1.2 | 30 (32.3) | 61 (43.0) | |
| 2.2 | 10 (10.7) | 18 (12.7) | |
| TGFB codon 10 (T/C) (rs1982073) | |||
| 1.1 | 34 (39.1) | 55 (39.0) | 0.4746 |
| 1.2 | 33 (37.9) | 62 (44.0) | |
| 2.2 | 20 (23.0) | 24 (17.0) | |
| TNF (G-238A) (rs361525) | |||
| 1.1 | 86 (92.5) | 129 (90.9) | 0.7369 |
| 1.2 | 7 (7.5) | 11 (7.7) | |
| 2.2 | 0 (0.0) | 2 (1.4) | |
| TNFα (G-308A) (rs1800629) | |||
| 1.1 | 56 (60.2) | 104 (73.2) | 0.0996 |
| 1.2 | 33 (35.5) | 35 (24.7) | |
| 2.2 | 4 (4.3) | 3 (2.1) | |
*
1.1, homozygous for the major allele; 2.2, homozygous for the minor allele; 1.2, heterozygous.