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. 2016 Mar 31;6:23670. doi: 10.1038/srep23670

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(a) Multiple protein sequence alignment of BMP family. Integrity identity; yellow. High similarity; green. (b) The tertiary structure was assembled using the mouse GDF5 sequence alignment. Amino acid 408 is highlighted in red. (c) Wild-type and GDF5^Rgsc451 (W408R) mice were evaluated using a micro-CT scanner. Scare bar: 5,000 μm.