Figure 2.

Glucose tolerance tests and insulin response to a glucose load. Glucose tolerance tests were performed as described in Materials and Methods. Briefly, mice were injected with 1.5 g/kg glucose and blood glucose concentration determined from tail vein blood samples every 15 min for 135 min. Panels A and B show the glucose curves and the area under the glucose curve (AUC), respectively. Panels C and D show the 30‐min blood glucose and insulin concentrations from a separate experiment following IP glucose injection. Results are presented as the means ± SE for a minimum of six animals/group analyzed individually. Significant differences are indicated (*as compared to the other three groups, ^#as compared to AL and YL, P < 0.05).