Table 1.

Patient characteristics

	Concurrent Cohorts 1 and 2/Schedule A	Alternating Schedule B	All patients
Number of patients	18	6	24
Age (years)
Median/range	60/43–70	54/44–63	58/43–70
Gender
Male	11 (60 %)	4 (67 %)	15 (63 %)
Female	7 (40 %)	2 (33 %)	9 (37 %)
Ethnicity
Caucasian			23 (96 %)
Other			1 (4 %)
Primary tumour
NSCLC	5	2	7
Esophageal	4		4
Pancreas	2	1	3
GU	4	2	6
Colon	2		2
Breast	1		1
Unknown		1	1

Number	Frequency	Percent
Previous treatment regimens
1	7	29.2
2	8	33.3
3	6	25.0
>3	3	12.5
Reason Off protocol
Progressive disease	19	79.2
Adverse event	1	4.2
Patient withdrawal	2	8.3
Other	2	8.3