Table 3. Distribution of Candidate Loss-of-Function Alleles in Genes with and without Homologs in Arabidopsis.

Mutation Type	Ancient Homolog		No Ancient Homolog		χ2	Pa
	Observed	Expected	Observed	Expected
Deletions	50	210	397	237	229.9	6.2 × 10−52
Partial deletions	48	258	501	291	322.5	4.2 × 10−72
All deletions	98	468	898	528	551.8	5.1 × 10−122
Nonsense (damaging)b	67	185	327	209	141.9	1.0 × 10−32
Nonsense (all)	154	336	560	378	186.2	2.1 × 10−42
Splice site	530	574	691	647	6.4	1 × 10−2

^aχ² test with 1 df.

^bNonsense mutations that prematurely truncate the protein by >25%.