Table 4.
Treatment | |||||||
---|---|---|---|---|---|---|---|
PLA | CrM | CrN-Low | CrN-High | Chi-Square | |||
Cholesterol | No Change | 0 | 0 | 0 | 0 | 0.33 | |
Normal Base; Exceed Day 7 | 10 | 8 | 12 | 13 | |||
Normal Base; Exceed Day 28 | 1 | 1 | 0 | 0 | |||
Normal Day7; Exceed Day 28 | 0 | 2 | 1 | 0 | |||
HDL-C | No Change | 6 | 9 | 10 | 10 | 0.72 | |
Normal Base; Exceed Day 7 | 2 | 1 | 0 | 0 | |||
Lipids & glucose | Normal Base; Exceed Day 28 | 1 | 0 | 1 | 1 | ||
Normal Day7; Exceed Day 28 | 2 | 1 | 2 | 2 | |||
LDL-C | No Change | 9 | 10 | 13 | 12 | 0.30 | |
Normal Base; Exceed Day 7 | 0 | 0 | 0 | 0 | |||
Normal Base; Exceed Day 28 | 2 | 1 | 0 | 0 | |||
Normal Day7; Exceed Day 28 | 0 | 0 | 0 | 1 | |||
Triglycerides | No Change | 11 | 11 | 13 | 13 | 0.31 | |
Normal Base; Exceed Day7 | 0 | 0 | 0 | 0 | |||
Normal Base; Exceed Day28 | 0 | 0 | 0 | 0 | |||
Normal Day7; Exceed Day28 | 0 | 0 | 0 | 0 | |||
Glucose | No Change | 10 | 9 | 11 | 11 | 0.56 | |
Normal Base; Exceed Day 7 | 1 | 1 | 1 | 0 | |||
Normal Base; Exceed Day 28 | 0 | 1 | 0 | 0 | |||
Normal Day7; Exceed Day 28 | 0 | 0 | 1 | 2 | |||
LDH | No Change | 9 | 9 | 12 | 11 | 0.26 | |
Normal Base; Exceed Day 7 | 1 | 0 | 0 | 0 | |||
Normal Base; Exceed Day 28 | 0 | 0 | 0 | 2 | |||
Normal Day7; Exceed Day 28 | 1 | 2 | 1 | 0 | |||
Creatine | No Change | 7 | 7 | 10 | 11 | 0.75 | |
Kinase | Normal Base; Exceed Day 7 | 2 | 1 | 1 | 0 | ||
Normal Base; Exceed Day 28 | 0 | 0 | 0 | 0 | |||
Normal Day7, Exceed Day 28 | 2 | 3 | 2 | 2 | |||
Muscle | Creatinine | No Change | 11 | 9 | 11 | 11 | 0.32 |
Normal Base; Exceed Day 7 | 0 | 0 | 0 | 0 | |||
Normal Base; Exceed Day 28 | 0 | 1 | 0 | 2 | |||
Normal Day7; Exceed Day 28 | 0 | 1 | 2 | 0 | |||
Kidney | BUN | No Change | 10 | 8 | 11 | 12 | 0.37 |
Normal Base; Exceed Day 7 | 0 | 0 | 1 | 0 | |||
Normal Base; Exceed Day 28 | 0 | 2 | 0 | 0 | |||
Normal Day7; Exceed Day 28 | 1 | 1 | 1 | 1 | |||
ALP | No Change | 11 | 11 | 13 | 13 | 0.32 | |
Normal Base; Exceed Day 7 | 0 | 0 | 0 | 0 | |||
Normal Base; Exceed Day 28 | 0 | 0 | 0 | 0 | |||
Normal Day7; Exceed Day 28 | 0 | 0 | 0 | 0 | |||
Liver | ALT | No Change | 11 | 9 | 12 | 11 | 0.49 |
Normal Base; Exceed Day 7 | 0 | 0 | 0 | 0 | |||
Normal Base; Exceed Day 28 | 0 | 2 | 1 | 2 | |||
Normal Day7; Exceed Day 28 | 0 | 0 | 0 | 0 | |||
AST | No Change | 8 | 8 | 12 | 8 | 0.54 | |
Normal Base; Exceed Day 7 | 1 | 0 | 1 | 0 | |||
Normal Base; Exceed Day 28 | 1 | 1 | 0 | 2 | |||
Normal Day7; Exceed Day 28 | 1 | 2 | 0 | 3 |
Data are presented as frequency. Statistical significance is detailed from chi-square analyses