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. 2016 Mar 31;16:24. doi: 10.1186/s12935-016-0299-0

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© Pera et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Assessment of the expression level of CACNA1H (Ca_v3.2) in SKBR3 derived trastuzumab-resistant cell lines, different breast cancer cell lines and non-malignant breast cell lines. Ca_v3.2 was not detected (ND) in non-malignant breast cell lines and the basal breast cancer cell lines MDA-MB-231 and MDA-MB-468. The luminal cell lines MCF-7 and T47D showed the highest expression of Ca_v3.2. Statistical analysis was performed within each subtype and trastuzumab-resistant cell lines were compared to the SV₁ trastuzumab sensitive SKBR3 cell line. For all amplified targets (n = 3 ±SD), statistical analysis was performed using one-way ANOVA with Bonferroni post-test (*p ≤ 0.05, **p ≤ 0.01)