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. 2016 Mar 31;17:146. doi: 10.1186/s12859-016-0994-9

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© Bi and Liu. 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Results from simulation 4. a Observed average power from different methods of differential expression analysis is plotted against the nominal FDR level controlled using the q-value procedure at sample size n=12. b Anticipated power curve calculated by ssizeRNA and observed power curves using voom and limma while FDR was controlled using either the Benjamini and Hochberg method (BH) or the q-value procedure by Storey and Tibshirani (ST)