Table 4.
Multivariable analysis examining relationship between clearance half-life or day 3 positivity and covariates kelch 13 propeller mutations, site and admission parasitaemia
| Odds ratio | 95 % confidence interval | P value | |
|---|---|---|---|
| Half-life cutoff 4 h | |||
| Site (Myitkyina) | 4.1 | 1.7–10.1 | 0.002 |
| Kelch 13 (>440) | 5.0 | 1.9–12.9 | 0.001 |
| Half-life cutoff 5 h | |||
| Site (Myitkyina) | 3.5 | 1.3–9.4 | 0.01 |
| Kelch 13 (>440) | 2.3 | 0.9–6.1 | 0.1 |
| Day 3 positivity | |||
| Parasitaemia on admission (>1 % parasitaemia) | 4.0 | 1.2–11.4 | 0.02 |
| Site (Myitkyina) | 3.2 | 1.1–9.6 | 0.04 |
| Kelch 13 (>440) | 2.0 | 0.7–4.0 | 0.68 |