Table 4.
Blood lipid, glucose and insulin concentrations in premenopausal women in a 1-year randomized controlled trial of weight gain prevention in which women were randomized to a registered dietitian-led nutrition education group (RDG), a counselor-led nutrition education group (CSG) or a control group (CON)
| Baseline | Month 3 | Month 6 | Month 9 | Month 12 | |||
|---|---|---|---|---|---|---|---|
| Variable | Group |
|
P-value | ||||
| Total cholesterol (mg/dL) | RDG (n = 26) | 169.0 ± 8.8 | 177.0 ± 9.5 | 178.7 ± 8.7 | 181.7 ± 8.8 | 175.8 ± 8.5 | Group = NS |
| CSG (n = 28) | 163.0 ± 6.0 | 176.8 ± 6.5 | 174.3 ± 5.9 | 178.0 ± 6.0 | 176.0 ± 5.8 | Time = NS | |
| CON (n = 24) | 156.2 ± 10.5 | 166.6 ± 11.3 | 170.4 ± 10.4 | 173.8 ± 10.6 | 160.7 ± 10.2 | G x T = NS | |
| High-density lipoprotein cholesterol (mg/dL) | RDG (n = 26) | 54.6 ± 3.7 | 54.1 ± 3.6 | 51.4 ± 3.4 | 53.1 ± 3.6 | 49.8 ± 3.7 | Group = NS |
| CSG (n = 29) | 52.5 ± 2.5 | 51.7 ± 2.4 | 51.6 ± 2.2 | 51.8 ± 2.4 | 50.4 ± 2.4 | Time = NS | |
| CON (n = 24) | 45.6 ± 4.4 | 45.8 ± 4.3 | 47.8 ± 4.0 | 48.9 ± 4.2 | 50.5 ± 4.4 | G x T = NS | |
| Low-density lipoprotein cholesterol (mg/dL) | RDG (n = 26) | 97.2 ± 7.0 | 104.1 ± 7.3 | 109.7 ± 7.1 | 111.5 ± 7.6 | 106.3 ± 6.8 | Group = NS |
| CSG (n = 28) | 96.9 ± 4.7 | 110.8 ± 5.0 | 107.8 ± 4.8 | 111.9 ± 5.1 | 111.5 ± 4.6 | Time = NS | |
| CON (n = 23) | 95.3 ± 8.5 | 111.9 ± 9.0 | 113.5 ± 8.6 | 111.8 ± 9.3 | 99.0 ± 8.3 | G x T = NS | |
| Triglycerides (mg/dL) | RDG (n = 25) | 54.2 ± 8.8 | 54.4 ± 7.7 | 56.4 ± 7.4 | 55.4 ± 8.7 | 62.2 ± 8.3 | Group = NS |
| CSG (n = 28) | 64.7 ± 5.8 | 63.4 ± 5.1 | 64.3 ± 4.9 | 68.1 ± 5.7 | 67.3 ± 5.5 | Time = NS | |
| CON (n = 22) | 86.0 ± 10.8 | 65.4 ± 9.4 | 62.9 ± 9.1 | 79.5 ± 10.6 | 73.0 ± 10.2 | G x T = NS | |
| Glucose (mg/dL) | RDG (n = 23) | 82.1 ± 4.7 | 84.6 ± 6.5 | 93.3 ± 2.3 | 96.7 ± 3.0 | 91.5 ± 2.8 | Group = NS |
| CSG (n = 25) | 87.4 ± 3.1 | 86.1 ± 4.4 | 92.2 ± 1.5 | 92.5 ± 2.0 | 91.8 ± 1.9 | Time = NS | |
| CON (n = 23) | 90.6 ± 5.3 | 80.0 ± 7.4 | 90.5 ± 2.6 | 88.2 ± 3.4 | 89.4 ± 3.1 | G x T = NS | |
| Insulin (μU/mL) | RDG (n = 25) | 4.5 ± 0.59 | 6.1 ± 0.82 | 4.9 ± 0.67 | 5.0 ± 0.57 | 3.0 ± 0.67 | Group = NS |
| CSG (n = 28) | 5.1 ± 0.40 | 5.9 ± 0.56 | 5.2 ± 0.46 | 5.3 ± 0.39 | 5.0 ± 0.45 | Time = NS | |
| CON (n = 21) | 5.2 ± 0.74 | 5.2 ± 1.00 | 5.6 ± 0.84 | 5.3 ± 0.71 | 8.0 ± 0.83 | G x T = NS | |
Fasting serum used to measure all biomarker concentrations
P-values using analysis of covariance, adjusted for baseline age, body weight and body mass index, with repeated measures on the time factor, using P < 0.01 for statistical significance; data presented as adjusted means ± standard error of the mean
G x T = group x time interaction; NS = not significant