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. 2016 Mar 30;17:58. doi: 10.1186/s13059-016-0901-8

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© Wang et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — IL23 downregulates CLDN8 in Caco-2 and NCM460 cells. a, b IL23 downregulates CLDN8 in NCM460 cells as quantitated by qPCR (a) and western blot (b). c, d IL23 downregulates CLDN8 in Caco-2 cells as quantitated by qPCR (c) and western blot (d). e IL23 decreases TEER. NC: cells treated with PBS. *P <0.05, **P <0.01, ***P <0.001