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Enrichment of improved‐affinity binders with consensus scoring. Plot showing the percentage of (A) all variants with observed ΔΔG < −1.0 kcal/mol or (B) SPM variants with observed ΔΔG < −0.5 kcal/mol found in the computationally rank‐ordered lists using rank‐by‐number, rank‐by‐rank, and rank‐by‐best consensus methods computed using FoldX and Discovery Studio predictions.
