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. 2015 Oct 22;25(2):374–382. doi: 10.1002/pro.2824

Figure 5.

Figure 5

Overview of no‐CaM simulation of the iNOS oxy‐FMN complex. (A) The same initial starting model, shown here in two different orientations, was used in the no‐CaM simulation as was used in the full oxy‐FMN‐CaM simulation. (B) The resulting equilibrated no‐CaM complex following 100 ns of simulation. Over the course of 100 ns, the FMN domain moved away from the heme domain and no tight interdomain complex was formed. All domains are colored identically as displayed in Figure 2.