(A) Median cell counts by cell type for new-onset type 1 diabetes patients (TrialNet) and healthy controls [National Health and Nutrition Examination Survey (NHANES)]. Error bars represent 95% confidence intervals. (B) Frequency of cell count abnormalities by Common Terminology Criteria for Adverse Events criteria and age group in type 1 diabetes TrialNet participants. White blood cell (WBC), grade 1 = 3000–lower limit of normal (LLN), grade 2 = 2500–3000; Lymphocytes, grade 1 = 800–LLN, grade 2 = 500–800; polymorphonuclear neutrophils (PMN), grade 1 = 1500–LLN, grade 2 = 1000–1500