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. 2015 Sep 16;19(3):pyv094. doi: 10.1093/ijnp/pyv094

Table 3.

Differences in Resting State Functional Connectivity between Controls and Adults with Attention-Deficit Hyperactivity Disorder (ADHD) at Baseline

Network and Regions MNI Coordinate Cluster Size (voxels)a Cluster-Level FWE- Corrected P b T Value Functional Connectivity (Rz), Mean (SD)
Control ADHD
Control>ADHD
Dorsal attention network
 Left FEF, right fusiform gyrus/inferior  temporal gyrus (BA 20/37) 42, -42, -12 289 .014 T=5.1 0.23 (0.18) -0.02 (0.14)
 Right FEF, right parahippocampal/fusiform gyrus 33, -39, -18 252 .032 T=4.18 0.21 (0.15) -0.01 (0.21)
 Right FEF, right middle frontal gyrus (BA 8) 18, 24, 45 293 .015 T=4.71 0.17 (0.18) -0.07 (0.21)
Cognitive control network
 Left DLPFC, precuneus/posterior  cingulate gyrus (BA 31/30)c -21, -36, -3 953 <.001 T=5.23 -0.29 (0.24) -0.02 (0.20)
 Right DLPFC, mPFC (BA 32/10)c,d 9, 48, -6 214 .053d T=4.74 -0.15 (0.16) 0.05 (0.16)
DMN
 Left PRE, right middle temporal/fusiform  gyrus (BA 20/21) 33, -9, -33 278 .02 T=4.59 0.29 (0.22) -0.01 (0.17)
ADHD and Control with reversed patterns in terms of positive and negative connections
Dorsal attention network
 Right FEF, left middle temporal/angular  gyrus (BA 39)c -39, -69, 15 277 .02 T=5.34 0.09 (0.17) -0.15 (0.16)
 Right FEF, left middle frontal gyrus (BA 8)c -30, 24, 39 234 .045 T=4.71 0.08 (0.14) -0.12 (0.18)

Abbreviations: BA, Brodmann area; DLPFC, dorsolateral prefrontal cortex; DMN, default mode network; FEF, frontal eye field; FWE, Family-wise error; MNI, Montreal Neurological Institute; mPFC, medial prefrontal cortex; PRE, precuneus; Rz, z-transformed Pearson’s correlational coefficient.

aThe normalized voxel was resampled to the size of isotropic 3mm.

bThe cluster-forming threshold was set at voxel-level P<.01.

cDifferences were displayed in negative functional connectivity between the 2 groups.

dTrend-level significance.