Table 2. The average nucleotide and amino-acid distances among the giant panda alleles from Aime-DRB1, Aime-DQA1, Aime-DQA2 and all Aime-DQA.
K2P nucleotide distance |
Poisson-corrected amino-acid distance |
||||
---|---|---|---|---|---|
All sites | ABS | Non-ABS | All sites | ABS | Non-ABS |
Aime-DRB1 | |||||
5.7 (1.0) | 20.7 (4.9) | 2.1 (0.7) | 10.5 (2.5) | 34.4 (9.5) | 4.8 (1.9) |
Aime-DQA1 | |||||
2.2 (0.7) | 7.5 (2.9) | 0.6 (0.4) | 4.0 (1.6) | 16.5 (7.4) | 0.5 (0.5) |
Aime-DQA2 | |||||
2.3 (0.7) | 9.0 (3.1) | 0.4 (0.3) | 4.5 (1.7) | 19.2 (7.6) | 0.4 (0.4) |
All Aime-DQA | |||||
3.4 (0.8) | 12.2 (3.6) | 1.0 (0.5) | 6.4 (2.1) | 25.3 (9.7) | 1.4 (1.0) |
Nucleotide distances are corrected for multiple substitutions with the Kimura 2-parameter model (K2P), and amino-acid distances are corrected using expectations from the Poisson distribution. ABS, putative antigen binding sites as determined in Reche and Reinherz (2003). Distances are given as percentages per site with standard errors (in parenthesis) based on 1000 bootstrap replicates.