Table 4. Results of generalized linear models (GLMs) for examining the associations of MHC class II alleles on parasite prevalence and infection intensity.
|
Prevalence |
Intensity |
|||||
|---|---|---|---|---|---|---|
| Δdeviance | d.f. | P-value | Δdeviance | d.f. | P-value | |
| Mountain | 8.27 | 4 | 0.082 | 1400.6 | 4 | 0.014 |
| Host gender | 0.006 | 1 | 0.940 | 153.5 | 1 | 0.230 |
| DRB1 | ||||||
| Aime-DRB1*8 | 0.207 | 1 | 0.649 | 57.108 | 1 | 0.460 |
| Aime-DRB1*9 | 0.517 | 1 | 0.472 | 73.859 | 1 | 0.398 |
| Aime-DRB1*10 | 3.268 | 1 | 0.071 | 1074.6 | 1 | <0.001 |
| Aime-DRB1*11 | 0.810 | 1 | 0.368 | 1.479 | 1 | 0.906 |
| Aime-DRB1*12 | 0.455 | 1 | 0.500 | 478.74 | 1 | 0.020 |
| Heterozygous | 0.721 | 1 | 0.471 | 240.670 | 1 | 0.144 |
| DQA1 | ||||||
| Aime-DQA*1 | 0.075 | 1 | 0.784 | 405.04 | 1 | 0.052 |
| Aime-DQA*3 | 1.988 | 1 | 0.159 | 663.51 | 1 | 0.010 |
| Aime-DQA*8 | 0.035 | 1 | 0.852 | 16.883 | 1 | 0.711 |
| Heterozygous | 2.409 | 1 | 0.121 | 366.55 | 1 | 0.064 |
| DQA2 | ||||||
| Aime-DQA*2 | 0.254 | 1 | 0.615 | 222.02 | 1 | 0.116 |
| Aime-DQA*5 | 2.941 | 1 | 0.086 | 96.621 | 1 | 0.315 |
| Aime-DQA*11 | 2.008 | 1 | 0.157 | 273.32 | 1 | 0.087 |
| Heterozygous | 4.625 | 1 | 0.045 | 262.73 | 1 | 0.085 |
Abbreviation: MHC, major histocompatibility complex.
Terms significant after the Bonferroni correction for the number of tested alleles are given in bold.
Effects of sampling area, host gender and heterozygous at the respective locus on parasite prevalence and intensity were fitted using GLMs, and then individual alleles that occurred in >5% were included singly in the GLMs with the other factors.