Table 1. Comparison of the clinical demographics between the two groups (n=90).
| Characteristics | Group 1: temporally tilted disc (n=47) mean±SD | Group 2: nontilted disc (n=44) mean±SD | P-value |
|---|---|---|---|
| Age (years) | 52±10.0 (31–88) | 69±9.1 (40–87) | <0.001a |
| Gender male/female | 30/17 | 19/25 | 0.04b |
| Follow-up period (months) | 108.2±32.5 | 112.4±43.6 | 0.61a |
| Spherical equivalent (D) | −4.9±1.2 (−7 to −3) | −0.1±0.5 (−0.7 to 0.7) | <0.001a |
| Number of topical medications | 1.4±0.5 (1–3) | 1.2±0.5 (1–3) | 0.16a |
| Baseline IOP (mm Hg) | 16.3±2.7 (10–21) | 15.8±2.5 (11–21) | 0.28a |
| Mean IOP (mm Hg) | 15.6±2.3 (12–19) | 14.4±2.0 (10.5–19.1) | 0.08a |
| Peak IOP (mm Hg) | 18.4±2.5 (14–21) | 17.6±2.3 (13–21) | 0.10a |
| Baseline mean RNFL thickness (μm) | 79.0±14.6 (48.7–106.1) | 79.4±13.9 (46.5–113.6) | 0.88a |
| Baseline mean CCT (μm) | 530.2±32.9 (482.0–614.0) | 519.0±36.8 (420.0–578.0) | 0.27a |
| Number of visual field tests | 10.7±3.1 (5–20) | 10.0±3.8 (6–24) | 0.07a |
| Baseline MD (dB) | −5.4±5.0 (−23.7 to 0.8) | −7.1±6.2 (−23.3 to 0.4) | 0.26a |
| Baseline PSD (dB) | 8.2±5.1 (1.6–16.8) | 8.0±4.8 (1.6–18.0) | 0.93a |
| Baseline VFI (%) | 85.5±14.8 (31–99) | 79.1±20.2 (22–100) | 0.15a |
| Progression rates of VFI by GPA (%/year) | −0.9±0.9 (−3.3 to −0.1) | −1.6±1.1 (−4.5 to −0.2) | 0.001a |
Abbreviations: CCT, central corneal thickness; GPA, glaucoma progression analysis; IOP, intraocular pressure; MD, mean deviation; PSD, pattern SD; RNFL, retinal nerve fiber layer; VFI, visual field index.
Statistically significant (P<0.05) for mean difference between two groups.
a
t-test, independent sample two-tailed t-test.
b
Pearson's χ2-test.