Table 3. Determination of the HRs for death from melanomaa using the Cox proportional hazards model: (A) patient outcome and (B) P-values and HRs.

(A) Patient outcomes
Histopathologic subtype	Dead	Alive	Total
Superficial spreading melanoma	7	27	34
Nodular melanoma	12	2	14
Acral lentiginous melanoma	2	4	6
Lentigo maligna melanoma	3	8	11
Mucosal lentiginous melanoma	2	1	3
Metastatic melanoma	14	6	20

(B) P-values and HRs
Histopathologic subtype	Nodular and metastatic melanomas P-value	HR	Superficial spreading and lentiginous melanomas P-value	HR	All melanomas P-value	HR	All melanomas P-value	HR	All melanomas P-value	HR
Age	0.5222	0.99	0.0044	1.07	0.0319	1.03	0.0785	1.02
eIF4E cytoplasmic histoscore	0.0616	2.22	0.4936	1.45	0.0342	2.01	0.0257	2.09	0.0323	2.03
eIF4E nuclear histoscore	0.8542	0.92	0.6083	1.36	0.6714	1.16	0.9856	1.01	0.836	0.93
p4E cytoplasmic histoscore	0.0052	3.66	0.8992	1.13	0.0031	2.78	0.0217	2.24	0.0555	2.01
p4E nuclear histoscore	0.0134	2.93	0.2533	2.00	0.0049	2.56	0.0132	2.31	0.0307	2.11
Adjusted	Age		Age		Age		Lesion subtype		Age, lesion subtype

Abbreviations: eIF4E=Eukaryotic translation initiation factor 4E; p4E=phosphorylated eukaryotic translation initiation factor 4E; HR=hazard ratio.

^aAdjusted for age and lesion histopathologic subtype.