Table 3. Summary of OS and hazard ratios.
Survival | Ford et al (2014) n (%) | Thuss-Patience et al (2011) n (%) | Kang et al (2012) n (%) |
---|---|---|---|
Total patient enrolment | 168 | 40 | 202 |
Number of events | 165 | 40 | 202 |
Median survival (95% CI) | |||
CT+SC | 5.2 (4.1–5.9) | 4.0 (2.6–5.6) | 6.3 (5.0–7.2) |
SC | 3.6 (3.3–4.4) | 2.4 (1.2–3.5) | 3.7 (2.7–4.5) |
Hazard ratio (95% CI) | 0.72 (0.53–0.98) | 0.48 (0.25–0.92) | 0.58 (0.43–0.78) |
P-value (two sided) | 0.04 | 0.02 | 0.0003 |
Abbreviations: CI=confidence interval; CT=chemotherapy; OS=overall survival; SC=supportive care.