Table 2. Primary treatment and response in patients with multiple myeloma.
| Low-IL-10 group, n (%) | High-IL-10 group, n (%) | P-value | |
|---|---|---|---|
|
Treatment | |||
| Treatment modalities | 0.542 | ||
| CT followed by ASCT | 36 (37.5) | 30 (32.6) | |
| CT alone | 60 (62.5) | 62 (67.4) | |
| Chemotherapy regimens | 0.080 | ||
| Bortezomib based | 49 (51.4) | 35 (38.0) | |
| DVD | 47 (48.6) | 57 (62.0) | |
|
Treatment response | |||
| CR | 25 (26.0) | 11 (12.0) | 0.016 |
| VGPR | 20 (20.8) | 16 (17.4) | 0.582 |
| ORR (⩾PR) | 76 (79.2) | 49 (53.3) | <0.001 |
Abbreviations: ASCT=autologous stem cell transplantation; CR= complete response; CT=chemotherapy; DVD=doxil, vincristine, and dexamethasone; IL-10=interleukin-10; ORR=overall response rate; PR=partial response; VGPR=very good partial response.