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. 2015 Oct 29;113(10):1484–1492. doi: 10.1038/bjc.2015.323

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Copyright © 2015 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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Enhanced TIM-4 expression in NSCLC shows poor prognosis. Immunohistochemical (IHC) staining was performed in 70 cases of NSCLC tissues and pericarcinoma tissues. (A) Representative IHC staining images of TIM-4 in NSCLC tissues and pericarcinoma issues (× 200). The negative control indicated that rabbit IgG replaced TIM-4 antibody in the process of IHC staining. (B) Staining intensity of TIM-4 in NSCLC tissues was significantly higher than that of the pericarcinoma tissues (P<0.0001). (C) The survival rate of lung cancer patients with higher TIM-4 expression was significantly lower than that of the patients with lower TIM-4 expression (P<0.0001).