Table 1. Pretreatment clinicopathologic characteristics of patients with cancer of the oesophagus or GOJ who underwent neoadjuvant chemo (radiation) therapy followed by transthoracic oesophagectomy with two-field lymphadenectomy.
| N | ||
|---|---|---|
| Number of patients | 394 | |
| Agea | 64.0 (23.37–79.85) | |
| Male | 293 (74.4%) | |
|
Histology | ||
| Adenocarcinoma | 302 (76.6%) | |
| Squamous cell | 92 (23.4%) | |
|
Tumour location | ||
| Mid-oesophagus | 43 (10.9%) | |
| Distal oesophagus | 160 (40.6%) | |
| GOJ | 191 (48.5%) | |
| Radicality of surgery RO:R1 | 386 (98%): 8 (2%) | |
| Number of resected nodes | 33 (10–77) | |
| Number of positive nodes | 1 (0–35) | |
|
Pretreatment clinical T stage/post-treatment ypT | ||
| cTx/ypT0 3 (0.8%) | 17 (4.3%) | |
| cT1/ypT1 | 3 (0.8%) | 48 (12.2%) |
| cT2/ypT2 | 21 (5.3%) | 75 (19%) |
| cT3/ypT3 | 346 (87.8%) | 238 (60.4%) |
| cT4/ypT4 | 21 (5.3%) | 16 (4.1%) |
|
Pretreatment clinical N stage/post-treatment ypN | ||
| cN0/ypN0 | 37 (9.4%) | 160 (40.6%) |
| cN1/ypN1 | 274 (69.5%) | 83 (21.1%) |
| cN2/ypN2 | 65 (16.5%) | 80 (20.3%) |
| cN3/ypN3 | 15 (3.8%) | 71 (18%) |
| cNx | 3 (0.8%) | |
Abbreviations: GOJ=gastro-oesophageal junction; R0=microscopically radical resection; R1=microscopically tumour left behind.
a
Values depicted are median (range).