Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 12;23(1):132–145. doi: 10.1038/cdd.2015.78

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

PMC Copyright notice

Decreased expression of miR-200 s and high target gene expression promote the activation of NFs to form CAFs. (a–d) Western blot analysis of α-SMA and FAP expression in the indicated engineered CAFs or NFs. β-Actin was used as a loading control. (e) Transwell chamber analysis of the invasion of CAFs transfected with miR-200 s vectors or of NFs transfected with shRNAs targeting the miR-200 s. The data are presented as the mean±S.D. (n=3; *P<0.05, ANOVA followed by the Student–Newman–Keuls test). (f) Transwell chamber analysis of the invasion of CAFs transfected with shRNAs targeting Fli-1 or TCF12 and of NFs transfected with Fli-1 or TCF12 vectors. The data are presented as the mean±S.D. (n=3; *P<0.05, Student's t-test)