Table 3. The T300A variants of ATG16L1 association with extraintestinal infections.

	GG risk variant	AA+AG genotype	P
Blood
E. coli	0.0008	0.0040	0.6
S. aureus	0.0044	0.0088	0.7
Klebsiella species	0.0062	0.0016	0.6
Urine
E. coli	0.0204	0.045	0.3
S. aureus	0.0177	0.0249	0.7
Klebsiella species	0.0088	0.0048	0.7
Enterococcus species	0.0151	0.0128	0.9
Streptococcus species	0.0071	0.008	0.9
Corynebacterium species	0.0008	0.0024	0.8
Feces
Salmonella species	0.0053	0.0056	0.97
Clostridium difficile	0.0044	0.0152	0.4
Airway (sputum)
S. aureus	0.0017	0.0016	0.98
Streptococcus species	0.0017	0	0.6
Haemophilus influenzae	0.0017	0.0064	0.6
Skin
S. aureus	0.0177	0.0152	0.9
Enterococcus species	0.0017	0	0.6
Streptococcus species	0.0035	0.0056	0.8

ATG16L1, autophagy-related 16-like 1.

AA, AG, and GG represent the genotype of ATG16L1.

The Z-test was used as a statistical tool for comparison of infectious risk by per patient-year. A two-tailed P value <0.05 was considered significant.