|
N (%) 256 EoE patients |
47 (18%) |
68 (27%) |
2 (1%) |
74 (29%) |
65 (25%) |
— |
| Mean age (years±s.d.) |
26±20 |
23±18 |
18±0.3 |
38±14 |
40±17 |
<0.001 |
| |
| Histology grade 3 (>15 eos/hpf) |
| Index proximal eosinophilia (%) |
72 |
75 |
100 |
84 |
74 |
0.833 |
| Index distal eosinophilia (%) |
74 |
93 |
100 |
83 |
95 |
0.366 |
| Last visit proximal eosinophilia (%) |
0 |
62 |
50 |
62 |
31 |
0.006 |
| Last visit distal eosinophilia (%) |
0 |
81 |
50 |
65 |
38 |
0.004 |
| |
| Clinical symptoms |
| Duration of symptoms (years±s.d.) |
6.5±7.6 |
4.2±5.0 |
2.6±0.8 |
8.0±7.1 |
8.2±8.3 |
0.013 |
| Follow-up time (years±s.d.) |
1.5±2.0 |
1.6±2.1 |
2.2±2.6 |
1.7±1.9 |
1.8±1.8 |
0.465 |
| Change in symptoms at follow-up |
|
|
|
|
|
<0.001 |
| % Patients improved symptoms |
72 |
54 |
0 |
69 |
69 |
|
| % Patients unchanged symptoms |
19 |
35 |
50 |
25 |
26 |
|
| % Patients worsened symptoms |
9 |
10 |
50 |
7 |
5 |
|
| |
|
|
|
|
|
|
| Treatment |
|
|
|
|
|
<0.001 |
| PPI only (%) |
15 |
12 |
0 |
22 |
9% |
|
| Intermittent topical steroid (%) |
23 |
31 |
0 |
54 |
58 |
|
| Continuous topical steroid (%) |
34 |
16 |
0 |
23 |
20 |
|
| Diet (%) |
28 |
41 |
100 |
1 |
12 |
|
