Table 1. Gene ontology analysis of genes selected during the first stage of dog domestication.
| GO category | number of genes | P value |
|---|---|---|
| Metabolism and motility | ||
| ATPase activity1 | 19 | 0.0056 |
| ATP binding1 | 55 | 0.0192 |
| Actin binding1 | 17 | 0.0195 |
| Nucleoside triphosphate metabolic process2 | 9 | 0.0208 |
| ATP metabolic process2 | 8 | 0.0211 |
| Phasic smooth muscle contraction2 | 3 | 0.0315 |
| Ribonucleotide metabolic process2 | 9 | 0.0385 |
| Purine nucleoside triphosphate metabolic process2 | 8 | 0.0399 |
| ATPase activity, coupled1 | 14 | 0.0402 |
| mRNA metabolic process2 | 17 | 0.0423 |
| Receptor metabolic process2 | 4 | 0.0448 |
| Drug metabolism3 | 8 | 7.82E-04 |
| Metabolism of xenobiotics by cytochrome P4503 | 7 | 0.0031 |
| ABC transporters3 | 6 | 0.0056 |
| Glutathione metabolism3 | 6 | 0.0075 |
| Retinol metabolism3 | 5 | 0.0452 |
| Neurological process and perception | ||
| Memory2 | 6 | 0.0034 |
| Regulation of sensory perception2 | 3 | 0.0315 |
| Regulation of sensory perception of pain2 | 3 | 0.0315 |
| Learning or memory2 | 8 | 0.0352 |
| Regulation of neurotransmitter levels2 | 6 | 0.0359 |
| Long-term memory2 | 3 | 0.0446 |
| Synaptic transmission2 | 14 | 0.049 |
| Long-term potentiation3 | 6 | 0.0291 |
| Sexual reproduction | ||
| Germ cell development2 | 7 | 0.0481 |
1Molecular function;
2Biological process;
3KEGG pathway